Lizzy Caplan
Biography
Elizabeth Anne Caplan (born June 30, 1982) is an American actress. Her performances as Virginia E. Johnson in the Showtime series Masters of Sex (2013–2016) and as Libby Epstein in FX on Hulu's Fleishman Is in Trouble (2022) have earned her nominations at the Primetime Emmy Awards.
Her first acting role was on the television series Freaks and Geeks (1999–2000). Since then, she had series-regular roles in several television series including Related (2005–2006), Party Down (2009–2010; 2023), Das Boot (2018), Castle Rock (2019), Truth Be Told (2019), Fatal Attraction (2023), and Zero Day (2025).
Caplan's film breakthrough came with her role as Janis Ian in Mean Girls (2004). Her other film appearances include My Best Friend's Girl (2008) Cloverfield (2008), Hot Tub Time Machine, 127 Hours (both 2010), Save the Date, Bachelorette (both 2012), The Interview (2014), Now You See Me 2, Allied (both 2016), and Cobweb (2023).
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Full filmography
- The Simpsons (1989) as Virginia Johnson (voice)
- Family Guy (1999) as Woman Arguing With Quagmire (voice)
- Smallville (2001) as Tina Greer
- American Dad! (2005) as Debbie (voice)
- Watch What Happens Live with Andy Cohen (2009) as Self - Guest
- The Tonight Show Starring Jimmy Fallon (2014) as Self
- Late Night with Seth Meyers (2014) as Self - Guest
- Conan (2010) as Self
- New Girl (2011) as Julia Cleary
- The View (1997) as Self
- True Blood (2008) as Amy
- Jimmy Kimmel Live! (2003) as Self
- Jimmy Kimmel Live! (2003) as Self - Guest
- Now You See Me: Now You Don't (2025) as Lula
- The Cleveland Show (2009)
- Masters of Sex (2013) as Virginia Johnson
- Tru Calling (2003) as Avery Bishop
- Childrens Hospital (2008) as Casey Klein
- Childrens Hospital (2008) as Harmony
- Close Up with The Hollywood Reporter (2015) as Self
- The League (2009) as Rebecca Ruxin
- Castle Rock (2018) as Annie Wilkes
- The Last Leg (2013) as Self
- Angie Tribeca (2016) as Deirdre