Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching H

A misanthropic author, a single mother and waitress, and a gay artist form an unlikely friendship after the artist is assaulted in a robbery. As Good as It Gets

Misanthropic novelist François writes gripping crime stories – “Agatha Christie meets The Scarlet Pimpernel” – but outside of the swashbuckling imaginary world

A young boy whose parents just divorced finds an unlikely friend and mentor in the misanthropic, bawdy, hedonistic, war veteran who lives next door. Comedy

Exposed to radioactive waste, small-time crook Enzo gains super-strength. A misanthropic, introverted brute, he uses his powers for personal gain until he meets

Probe is a 1988 American television pilot and subsequent TV series, created by television mystery writer William Link and noted science fiction author Isaac Asi

A rich farmer is well known for being very unkind. He's misanthropic, misogynous and cantankerous. Until he meets by chance a gorgeous girl... Comedy

When a man is diagnosed with terminal cancer, he takes custody of his misanthropic teenage son, for whom quality time means getting high, engaging in small-time

During the Klondike Gold Rush, a misanthropic cattle driver and his talkative elderly partner run afoul of the law in Alaska and are forced to work for a saloon

A heartbroken literary critic turns his despair into creativity following a bitter divorce, only to encounter an enchanting beauty who poses a major challenge t