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Season guide

House: Season 4

16 episodes Premiered Sep 25, 2007
Previously on House

Season 4 Lore Primer

Key plot threads, lore context, and character stakes you need to remember before diving into this season.

  • Directly follows the overarching narrative developments of House Season 3.
  • Faction dynamics and core character alliances shift under escalating external stakes.
  • Crucial mysteries introduced previously reach key turning points and narrative reckonings.
  • Sets up serialized story arcs that build directly toward the climactic season finale.
Season 4 Episodes

Episode Guide

🛡️ SPOILER SHIELD

Season 4 Progress Shield

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Binge Efficiency Engine

Season 4: Filler vs. Essential Canon

Filter episodes by narrative weight. Focus on essential mytharc and skip standalone side quests.

19%
81%
Mytharc (3): Crucial lore & season climaxes
Core (13): Character development & subplots
Side Quest (0): Standalone / filler
S4·E1 Mytharc

Alone

Sep 25, 2007

With his diagnostic team gone, House tries to diagnose a young woman who survived an office building collapse. With the condition getting worse, Cuddy puts pressure on House to hir

S4·E2 Core

The Right Stuff

Oct 2, 2007

House is secretly trying to treat a fighter pilot who is a candidate for NASA's astronaut training program. Her diagnosis will be the test to choose which ones of the 40 applicants

S4·E3 Core

97 Seconds

Oct 9, 2007

The candidates are now two teams of five women and five men, competing on diagnosing and treating a wheelchair-bound man. Meanwhile House does experiments on himself to test what h

S4·E4 Core

Guardian Angels

Oct 23, 2007

House finds that some of his own fellowship students will do whatever it takes, when they deal with a woman who believes she can talk to the dead.

S4·E5 Core

Mirror Mirror

Oct 30, 2007

House deals with a patient who mirrors the personality of anyone he meets. Meanwhile, Foreman is put in charge of overseeing the fellowship candidates.

S4·E6 Core

Whatever It Takes

Nov 6, 2007

Based on practically no information and no medical history about a mystery patient sent by the CIA, House is using some unorthodox methods to diagnose and treat him. Meanwhile the

S4·E7 Core

Ugly

Nov 13, 2007

A film crew and the candidates are following around House distracting him while he is trying to diagnose a teenager who suffers from a heart attack prior to a serious plastic surge

S4·E8 Core

You Don't Want to Know

Nov 20, 2007

House treats a magician but comes to believe he's faking illness to cover up his own incompetence. Meanwhile, House pits the fellows against each other in his version of an immunit

S4·E9 Core

Games

Nov 27, 2007

Under Cuddy’s pressure to choose his team, House gives the candidates a case of a former punk rock star who is a drug user. Whoever diagnoses the patient is going to have a future

S4·E10 Core

It's a Wonderful Lie

Jan 29, 2008

A mother's sudden paralysis during a indoor rock-climbing incident leaves her daughter injured, and House's new team looking for a cure. Meanwhile, House organizes his new recruits

S4·E11 Core

Frozen

Feb 3, 2008

House and his team have to diagnose a case at a distance when a researcher at a South Pole base is taken ill.

S4·E12 Core

Don't Ever Change

Feb 5, 2008

House and his team must diagnose a Jewish bride who is taken ill at her wedding. However, House is more interested in analyzing Wilson's relationship with his new girlfriend.

S4·E13 Core

No More Mr. Nice Guy

Apr 28, 2008

House copes with a patient whose symptoms conceal a greater problem, but spends much of his time dodging Cuddy's orders to give performance reviews, and fighting with Amber over wh

S4·E14 Core

Living the Dream

May 5, 2008

House is convinced one of the actors on his favorite soap opera “Prescription Passion” has a serious medical condition after observing his symptoms on television. House decides to

S4·E15 Mytharc

House's Head (1)

May 12, 2008

A bus accident leaves House with serious head trauma and partial amnesia. He comes to believe that a patient on the bus had a life-threatening disease and struggles to recall who i

S4·E16 Mytharc

Wilson's Heart (2)

May 19, 2008

In the aftermath of the bus accident, House struggles with his head injuries and short-term memory loss, and must deal with a concerned Wilson who believes his friend's health may