Holby City: Series 21
Season 21 Lore Primer
Key plot threads, lore context, and character stakes you need to remember before diving into this season.
- Directly follows the overarching narrative developments of Holby City Season 20.
- Faction dynamics and core character alliances shift under escalating external stakes.
- Crucial mysteries introduced previously reach key turning points and narrative reckonings.
- Sets up serialized story arcs that build directly toward the climactic season finale.
Episode Guide
Season 21 Progress Shield
Everything Old Is New Again
Jan 2, 2019 · 60 min
Jac, Ric and Sacha face off against old rivals while pitching for a million-pound prize fund. But as the competition threatens to divide the group, should they be more worried abou
China Crisis
Jan 8, 2019 · 60 min
A surprise blast from the distant past returns to run a Young Adult Unit alongside top consultant Ange Godard. He successfully puts everyone on tenterhooks with his notorious barbs
The Burden of Proof
Jan 15, 2019 · 60 min
Ange finally allows Dominic the chance to work on her new unit, after much persistence, but she isn't sure whether he has the chops to be a great doctor. When Dominic is economical
A Daring Adventure or Nothing at All
Jan 22, 2019 · 60 min
Frieda is happy her life is on an even keel, but her contentment is shattered when her ex-boyfriend Roman unexpectedly reappears. Can a wary Frieda open her heart and dare to imagi
Mad as Hell
Jan 29, 2019 · 60 min
When Holby is overwhelmed by a winter crisis, Ric goes above and beyond to treat his patients. But as the pressure reaches fever pitch, can he continue to accept Holby surviving on
Force Majeure
Feb 5, 2019 · 60 min
When a family secret is exposed, the dispute causes a young patient to delay vital surgery, but fearing the consequences of such a decision, a concerned Ange must find a way to mak
Good Side
Feb 12, 2019 · 60 min
While Holly's condition weighs heavily on an emotionally invested Ange, Holly's distraught parents must put their differences aside to make a heartbreaking decision, but are they p
Never Say Never
Feb 19, 2019 · 60 min
Zosia arrives at Holby keen to get back working on Darwin. With her knack for irritating Jac in full swing, will Jac be able to track down Frieda before Zosia gets too comfortable?
Guts
Feb 26, 2019 · 60 min
Zosia's big news gets a mixed response, and Jac remains suspicious about her real reasons for returning to Holby. Zosia's situation is further complicated when a handsome American
Powerless
Mar 5, 2019 · 60 min
A computer virus shuts down Holby’s power, putting Jac and Connie at loggerheads as they fight against all odds and in makeshift conditions to save the lives of close friends and c
A Simple Lie (1)
Mar 19, 2019 · 60 min
A desperate Ange pleads with Holly’s family to see reason, but when the ruling comes back, the anger finally boils over with devastating consequences for Fletch. Ric's son Kofi arr
A Simple Lie (2)
Mar 20, 2019 · 60 min
As the protesters grow angrier Holby tightens security, Fletch realises there may be darker forces at play with Theo’s disappearance. Chloe struggles to decide if staying at Holby
Running
Mar 26, 2019 · 60 min
Ange follows a hunch and ends up uncovering a shocking and long buried secret – one with the potential to tear her life completely apart. A downbeat Frieda faces tough choices whe
Ask No Questions
Apr 2, 2019 · 60 min
Chloe is surprised and immediately wrongfooted when ex-boyfriend Evan unexpectedly turns up on Darwin Ward. Is it possible he’s simply there to care for his sister Phoebe? As Ange
The Family Way
Apr 9, 2019 · 60 min
A bewildered Dom struggles to come to terms with a shocking family secret and he immerses himself in work. However being around Ange proves difficult, causing Dom to make a drasti
North and South
Apr 16, 2019 · 60 min
A startling incident forces Zosia to reconsider her future at Holby, Cameron has to treat a close relative of Xavier's, and Dom tries to keep Carole at arm's length.
Pleased to Meet You
Apr 23, 2019 · 60 min
Jac’s top-dog status is challenged when a talented new surgeon starts at Holby and instantly causes a stir. Dom is irritated when Carole starts work on reception, and Ange tries to
Vinegar and Honey
Apr 30, 2019 · 60 min
Kian’s big personality and alternative methods are beginning to grate on Jac, but is it just a case of professional jealousy? Fletch reminds her that she’s only as good as her team
Ex Marks the Spot
May 7, 2019 · 60 min
Ange plans to tell Chloe her biggest secret, but a surprise locum throws her day into disarray. Ric’s granddaughter, Darla, arrives at Holby, forcing Ric to deal with her pregnancy
The Wrong Horse
May 14, 2019 · 60 min
As Chloe tries to come to terms with the news that Dominic is her half-brother, she’s forced to operate with him and Ange. But as tension boils over and Evan helps her uncover a ho
Unredeemed
May 21, 2019 · 60 min
Dominic faces his difficult past when he goes head to head with his abusive ex, Isaac. Ange and Carole band together in order to cope with the fact that Isaac has returned, affecti
Bloodline
May 28, 2019 · 60 min
Will Lofty and Dom’s marriage survive under the pressure of Isaac’s presence at Holby, and is Sacha’s relationship with Patricia over before it’s even begun?
In the Right Place
Jun 4, 2019 · 60 min
As Dom and Isaac grow closer, is Dom at risk of falling under his spell? Hanssen finds himself in unfamiliar territory when an estranged relative arrives at Holby, and Chloe gets a
Over My Dead Body
Jun 11, 2019 · 60 min
The manipulative Isaac continues to drive a wedge between Dom and Lofty, but when Isaac puts Lofty in harm’s way and the net is closing in, is Isaac’s fate sealed? Good intentions
Pigeon
Jun 20, 2019 · 60 min
When Xavier’s mum arrives on AAU talking in riddles, Donna does her best to shelter him from her behaviour - but will he appreciate the intervention? Sacha makes a romantic gesture
Kiss Kiss
Jun 25, 2019 · 60 min
Xavier tries to build bridges with Donna, but she’s having none of it. Cameron can’t quite shift his feelings of unease around Evan, and when he overhears a phone call his suspicio
Flying Solo
Jul 9, 2019 · 60 min
Cameron tries to prove himself to Kian, but they clash over Kian's teaching methods. A frustrated Xavier gets relationship advice from the most unlikely source, and Carole opens up
Reckless
Jul 10, 2019 · 60 min
Chloe’s day is thrown into chaos when Evan is attacked. With his life on the line, Evan asks Chloe a surprising question. Dominic is put under pressure when a surprise visitor arri
Honeymoon
Jul 16, 2019 · 60 min
As her loved ones continue to worry about her, Chloe learns more about Evan. Cameron wants to get out from under Bernie’s shadow, but he receives some devastating news. Hanssen lea
Don't Leave Me
Jul 23, 2019 · 60 min
On the anniversary of a personal tragedy, Kian decides he must save a life today. Hanssen worries that with his family history he shouldn’t look after Oskar and wonders whether nat
Things My Mother Told Me
Jul 30, 2019 · 60 min
As the Holby team give a warm send off to a much beloved colleague, a surprising revelation sends Cameron into a spin. However, Cameron crosses the line when his drunken behaviour
When Worlds Collide
Aug 6, 2019 · 60 min
Jac’s work-life balance is called into question when her ex’s new fiancee arrives at Holby with Emma in tow, and she’s forced to make a career changing decision. Will life on Darwi
Work-Life Balance
Aug 13, 2019 · 60 min
Is Chloe brave enough to tell Evan she wants a divorce? And what will he do if she does? Faced with choosing between work and his personal life, will Hanssen learn from past mistak
Where Does It Hurt?
Aug 20, 2019 · 60 min
A distressed stranger turns up looking for Raf di Lucca. Will her secret change Essie’s life forever? Xav questions Ric’s competence, but is Ric’s outrage hiding a graver concern?
Babysitters and Bystanders
Aug 27, 2019 · 60 min
Chloe's day is thrown into chaos when Evan's sister, Phoebe, returns to Holby. Essie is left torn when she is forced to make a difficult decision, and a high profile patient is adm
The Perfect Storm
Sep 3, 2019 · 60 min
Jac is rocked when Faye Morton returns to Holby bringing Joseph with her. Sacha struggles to do the right thing for a family grieving their mother.
Gods and Monsters
Sep 10, 2019 · 60 min
A friendly face from the past gives Ric someone to confide in. Fletch goes on a mission that could cost him his relationship with Ange.
Circle of Life
Sep 17, 2019 · 60 min
Fearing something may be wrong with him, Ric is absent when his granddaughter, Darla, goes into early labour. When Isla requires emergency surgery, Essie’s lie that she’s her adopt
Retreat
Sep 24, 2019 · 60 min
Evan refuses to give up on Chloe and proves what a real threat he can be. Cameron abandons his quest to help Ric when he receives heart-breaking news.
Divine Justice
Oct 1, 2019 · 60 min
Will it be Chloe or Evan’s version of events that will be believed? How can a grieving Cameron make amends for failing Chloe when she needed him most? And what will an MRI scan rev
This Be the Verse
Oct 8, 2019 · 60 min
Both Ric and Darla are faced with life-changing decisions, an aggressive stranger at the hospital threatens to blow Essie’s baby secret wide open, and will Kian be able to mend the
Hope is a Powerful Drug
Oct 15, 2019 · 60 min
Essie is torn when Frankie returns wanting to take Isla home, Ric is caught between Serena and top neurosurgeon Max McGerry as they clash over his treatment options, and Jac return
Promise
Oct 22, 2019 · 60 min
Max performs dangerous brain surgery on Ric, who must confront his own mortality. Dom is shocked when Helen returns to Holby and Lofty finds out she’s pregnant.
Hubble Bubble
Oct 29, 2019 · 60 min
It’s Halloween and Cameron is haunted by his own ghosts. Jac receives a bombshell from Stacey, and will Dominic overstep the mark when it comes to Lofty’s baby?
Remember, Remember
Nov 5, 2019 · 60 min
In Holby City’s 1,000th episode, Jac is due to perform a milestone surgery, but will personal issues cloud her judgement? It’s Holby City Hospital’s 150th birthday and a familiar f
Sandra's Choice
Nov 12, 2019 · 60 min
As Elliot’s concern for Jac grows, will he ever be able to tell her his secret? Lofty is determined to be there for his new family, but will it be smooth sailing from here? Sacha i
We Are All the Stars
Nov 19, 2019 · 60 min
A heartbroken Lofty and Helen are rocked by tragic news which tears their world apart. A guilty Xavier evaluates his working relationship with Donna, and are the cards stacked agai
Blurring the Lines
Nov 26, 2019 · 60 min
Kian is desperate to deliver the surgery that Bea desires, but stressed Jac won’t play ball. How much will Kian sacrifice to give Bea what she wants? Dom and Lofty are too busy put
Bell Jar
Dec 3, 2019 · 60 min
Elliot needs life-saving surgery. Jac is the only one qualified to do it, but will her struggles with anxiety result in her killing her mentor? Cameron sees an opportunity to make
Kintsugi
Dec 10, 2019 · 60 min
Jac has to face some home truths in the Psychiatric Unit when she's visited by the three wise men. Chloe gets some life-changing news that she has to share with Evan's sister, Phoe
Lemons
Dec 17, 2019 · 60 min
On the day he and Dom are due to renew their wedding vows, Lofty finally makes a decision about what he really wants in life. A newly pregnant Chloe wrestles with her conscience, a
Be True, Be Brave, Be Kind
Dec 19, 2019 · 60 min
When Bea requires emergency surgery, a suspended Kian takes matters into his own hands, but at what cost? Essie’s feathers are ruffled by a flash new consultant, and how will Domin
Mothers and Their Daughters
Dec 31, 2019 · 60 min
Confronted with an unwelcome patient, Serena is forced to make a life or death choice. Chloe decides she’s ready to move on in 2020, but will her decision hurt a good friend? And A