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Season guide

The Megan Mullally Show: Season 1

76 episodes Premiered Sep 18, 2006 Updated Jul 21, 2026

Season 1 Episodes

Episode Guide

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Season 1 Progress Shield

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Season 1: Filler vs. Essential Canon

Filter episodes by narrative weight. Focus on essential mytharc and skip standalone side quests.

96%

Mytharc (3): Crucial lore & season climaxes

Core (73): Character development & subplots

Side Quest (0): Standalone / filler

S1·E1 Mytharc

Will Ferrell, Jenny McCarthy

Sep 18, 2006 · 43 min

S1·E2 Core

Eva Mendes, "So You Think You Can Dance", Granny Basketball

Sep 19, 2006 · 60 min

S1·E3 Core

Lisa Kudrow, 10 year-old Opera Singer, Adam Rodriguez

Sep 20, 2006 · 60 min

S1·E4 Core

Carol Burnett, Rainn Wilson, Hollerin' Championships

Sep 21, 2006 · 60 min

S1·E5 Core

Felicity Huffman, 'Animal Guys' Paul Hahn and David Riherd, Enrique Murciano

Sep 22, 2006 · 60 min

S1·E6 Core

Julia Louis-Dreyfus, Illusionist Criss Angel, Mario Lopez

Sep 25, 2006 · 60 min

S1·E7 Core

Debra Messing, Fashion Makeover with Lucky Magazine, Omar Epps

Sep 26, 2006 · 60 min

S1·E8 Core

George Lopez, Jennifer Finnigan, Vacuum Cleaning Genius, Tim Bagley At A Cher Convention

Sep 27, 2006 · 60 min

S1·E9 Core

Sela Ward, Chris Noth

Sep 28, 2006 · 60 min

S1·E10 Core

Patricia Heaton, Duane Martin, Jesse McCartney

Sep 29, 2006 · 60 min

S1·E11 Core

Jane Kaczmarek, Masi Oka, Champion Cloggers

Oct 2, 2006 · 60 min

S1·E12 Core

Tom Bergeron, Eric Stromer, Elizabeth Perkins

Oct 3, 2006 · 60 min

S1·E13 Core

Tim Daly, Domino Magazine

Oct 4, 2006 · 60 min

S1·E14 Core

Connie Britton, Michael Clark Duncan

Oct 5, 2006 · 60 min

S1·E15 Core

Jennifer Love Hewiitt, Jonny Lee Miller, J. Xavier

Oct 6, 2006 · 60 min

S1·E16 Core

Virginia Madsen, Noah Gray-Cabey, Around The Office

Oct 9, 2006 · 60 min

S1·E17 Core

Marcia Cross, Clinton Kelly, Isaiah Washington

Oct 10, 2006 · 60 min

S1·E18 Core

Molly Ringwald, OK Go

Oct 11, 2006 · 60 min

S1·E19 Core

Wanda Sykes, Goran Visnjic, Ruben Studdard

Oct 12, 2006 · 60 min

S1·E20 Core

Peter Gallagher, Nathan Burton, Tyler James Williams

Oct 13, 2006 · 60 min

S1·E21 Core

Bradley Whitford, Shelley Morrison, Eric Mabius, Mario Vazquez, Phil Pfister

Oct 16, 2006 · 60 min

S1·E22 Core

Cheyenne Kimball, Laura Linney, Ricardo Antonio Chavira

Oct 17, 2006 · 60 min

S1·E23 Core

Merv Griffin, Kim Raver, Author Jennifer Egan

Oct 18, 2006 · 60 min

S1·E24 Core

Rob Morrow, Rebecca Cole, Anne Heche, Joshua Bell

Oct 19, 2006 · 60 min

S1·E25 Core

Josh Duhamel, Alison Lohman, Authors Mark Leyner and Billy Goldberg, Aly & AJ Michalka

Oct 20, 2006 · 60 min

S1·E26 Core

Kristin Chenoweth, Jill Conner Browne, Nick & Aaron Carter, the Sweet Potato Queens

Oct 23, 2006 · 60 min

S1·E27 Core

Jamie Lee Curtis, The Mystic Pixies, Amy Smart, Taylor Swift

Oct 24, 2006 · 60 min

S1·E28 Core

Lauren Holly, Ruben Studdard, Daniel Dae Kim

Oct 25, 2006 · 60 min

S1·E29 Core

Cloris Leachman, Jensen Ackles, Dog Halloween Costumes with Teri Austin, ecostylist Danny Seo

Oct 26, 2006 · 60 min

S1·E30 Core

James Denton, Yahoo 9's Maria Sansone, Angela Kinsey, JoJo

Oct 27, 2006 · 60 min

S1·E31 Core

Steven Weber, Audra McDonald

Oct 30, 2006 · 60 min

S1·E32 Core

Neil Patrick Harris, Kevin Federline

Oct 31, 2006 · 60 min

S1·E33 Core

Jamie Kennedy, Jeffrey Sebelia, Meat Loaf, Card Thrower Rick Smith

Nov 1, 2006 · 60 min

S1·E34 Core

Clay Aiken, Tysonia Tschinga "Real Life" Dancing with the Stars

Nov 2, 2006 · 60 min

S1·E35 Core

Sean Hayes, Eddie Cibrian, Dog Whisperer Cesar Millan, Author Mitch Albom

Nov 3, 2006 · 60 min

S1·E36 Core

Barry Manilow, Parminder Nagra, Tim Bagley visits "America's Got Talent", Kid's Ballroom Dancing

Nov 6, 2006 · 60 min

S1·E37 Core

Mark Harmon, Hip Hop Champions, Constance Zimmer, Melora Hardin

Nov 7, 2006 · 60 min

S1·E38 Core

Kevin Nealon, Antonio Sabato Jr.

Nov 8, 2006 · 60 min

S1·E39 Core

Bob Saget, sex educator Sue Johanson

Nov 9, 2006 · 60 min

S1·E40 Core

Molly Sims, Andrea Bowen, The Ten Tenors, Celebrity trainer Michael Carson

Nov 10, 2006 · 60 min

S1·E41 Core

Cheryl Hines, Tim Gunn, Thanksgiving Dog Adoption Fashion Show

Nov 13, 2006 · 60 min

S1·E42 Core

David Hyde Pierce, Linda Cardellini, Taylor Ware

Nov 14, 2006 · 60 min

S1·E43 Core

Patricia Arquette, Champion Pirouette Dancer, Daily Candy Trends

Nov 15, 2006 · 60 min

S1·E44 Core

Dax Shepard, Tom Arnold, Kimberley Locke

Nov 16, 2006 · 60 min

S1·E45 Core

Reba McEntire, Patrick Wilson, RBD

Nov 17, 2006 · 60 min

S1·E46 Core

Tom Bergeron, Trista and Ryan, Benji Schwimmer, Rupert Boneham

Nov 20, 2006 · 60 min

S1·E47 Core

Sharon Stone, Scott Foley, Rusty Schwimmer, Paz Vega, Danny Seo

Nov 21, 2006 · 60 min

S1·E48 Core

Wayne Brady, Penguins Pete and Penny, Nestle Toll House Bake Sale Finalist

Nov 22, 2006 · 60 min

S1·E49 Core

Camryn Manheim, Phil Pfister, James Lesure, Author Karen Rizzo

Nov 24, 2006 · 60 min

S1·E50 Core

Neil Patrick Harris, Josh Radnor, Alyson Hannigan, Jason Segel and Cobie Smulders

Nov 27, 2006 · 60 min

S1·E51 Core

David Boreanaz, Julianne Nicholson, Bianca Ryan

Nov 28, 2006 · 60 min

S1·E52 Core

Matthew Broderick, Donald Faison, Brian Baumgartner, the Bucket Boys, Catherine Lloyd Burns

Nov 29, 2006 · 60 min

S1·E53 Core

Tracy Morgan, Melissa Peterman, Jarod Miller, Eric Stromer

Nov 30, 2006 · 60 min

S1·E54 Core

Carrie Fisher, Paul Rodriguez, Nadine Velazquez

Dec 1, 2006 · 60 min

S1·E55 Core

Rosanna Arquette, Tom Green, Adrian Pasdar

Dec 4, 2006 · 60 min

S1·E56 Core

Marla Sokoloff, Taylor Hicks, "Campus Ladies"

Dec 5, 2006 · 60 min

S1·E57 Core

Phyllis Diller

Dec 6, 2006 · 60 min

S1·E58 Core

Carson Kressley, Beau Bridges, Amy Sedaris

Dec 7, 2006 · 60 min

S1·E59 Core

Wendie Malick, Janice Dickinson

Dec 8, 2006 · 60 min

S1·E60 Core

John Stamos, Brenda Strong, Cris Judd, Tyrese

Dec 11, 2006 · 60 min

S1·E61 Core

David James Elliott, Michael Ealy, Lisa Edelstein, magician Nathan Burton

Dec 12, 2006 · 60 min

S1·E62 Core

Jeffrey Tambor, Tisha Campbell, designer Mark Montano, Hall & Oates

Dec 13, 2006 · 60 min

S1·E63 Core

Shawn and Marlon Wayans, Taylor Hicks

Dec 14, 2006 · 60 min

S1·E64 Core

Oded Fehr, Rob Morrow, Rhea Perlman, Sarah Rush

Dec 15, 2006 · 60 min

S1·E65 Core

Howie Mandel, Jennie Garth, Ahmet Zappa, psychic medium Lisa Williams

Dec 18, 2006 · 60 min

S1·E66 Core

Jane Seymour, David Conrad, Ken Davitian, Joshua Radin

Dec 19, 2006 · 60 min

S1·E67 Core

Alfre Woodard, Milo Ventimiglia, Fantasia Barrino

Dec 20, 2006 · 60 min

S1·E68 Core

Billy Ray Cyrus, Richard Simmons, authors of "Party Confidential"

Dec 21, 2006 · 60 min

S1·E69 Core

Hall & Oates, Brian McKnight, Clay Aiken, José Feliciano, Kimberley Locke, Celtic Woman

Dec 22, 2006 · 60 min

S1·E70 Core

Emily Procter, Tichina Arnold, Goo Goo Dolls

Jan 8, 2007 · 60 min

S1·E71 Core

Natalie Cole, Craig Bierko, Dave Annable, Blaine Zuckerman

Jan 9, 2007 · 60 min

S1·E72 Core

Tom Bergeron, Tim Daly, Will Ferrell, Allison Janney, Davy Jones, Chris Noth, Jerry Springer

Jan 15, 2007 · 60 min

S1·E73 Core

Patricia Heaton, Cheryl Hines, Debra Messing, Christine Taylor

Jan 16, 2007 · 60 min

S1·E74 Core

Josh Duhamel, Jamie Kennedy, George Lopez, Mario Lopez

Jan 17, 2007 · 60 min

S1·E75 Mytharc

Selma Blair, Kristin Chenoweth, Lisa Kudrow, Laura Linney, Julia Louis-Dreyfus

Jan 18, 2007 · 60 min

S1·E76 Mytharc

Chandra Wilson, Jesse Bradford, Clay Aiken

Jan 24, 2007 · 60 min