The Drew Barrymore Show: Season 6
Season 6 Lore Primer
Key plot threads, lore context, and character stakes you need to remember before diving into this season.
- Directly follows the overarching narrative developments of The Drew Barrymore Show Season 5.
- Faction dynamics and core character alliances shift under escalating external stakes.
- Crucial mysteries introduced previously reach key turning points and narrative reckonings.
- Sets up serialized story arcs that build directly toward the climactic season finale.
Episode Guide
Season 6 Progress Shield
Valerie Bertinelli; Catherine Zeta-Jones
Sep 8, 2025
Catherine Zeta-Jones joins Drew for the Season 6 premiere to tell her all about the exciting second season of "Wednesday"; Drew covers the headlines with pals Ross Mathews and Vale
Halle Berry; Kristina Zias
Sep 8, 2025
Drew, Halle Berry and Kristina Zias celebrate aging by helping a viewer over 50 achieve a glow-up look.
Halle Berry; Nate Burleson; Valerie Bertinelli; Melani Sanders
Sep 9, 2025
Halle Berry, Valerie Bertinelli, viral sensation Melani Sanders and Nate Burleson join Drew for a Fearless After 50 roundtable discussion.
Issa Rae
Sep 9, 2025
Issa Rae tells Drew about her new book, "I Should Be Smarter by Now," and upcoming two-part docuseries, "Seen & Heard."
Valerie Bertinelli; Pilar Valdes
Sep 10, 2025
Valerie Bertinelli joins Drew and Ross Mathews to hit the headlines; Drew tells a special Adam Sandler story in honor of his birthday; Pilar Valdes has some easy advice for a week
Michael and Cameron Douglas
Sep 10, 2025
Drew chats with father-son duo Michael and Cameron Douglas.
David Letterman
Sep 11, 2025
Drew sits down with David Letterman, who plays a round of memory bank and shares his memories of some of his most iconic moments.
Sunny Anderson
Sep 11, 2025
Sunny Anderson covers the headlines with Drew and Ross and provides suggestions for decluttering your closet and an easy dip recipe.
Sunny Anderson; Emeril Lagasse
Sep 12, 2025
Sunny Anderson gets a big surprise from Drew: cooking with the legendary Emeril Lagasse!
Jennifer Aniston
Sep 12, 2025
Drew chats with Jennifer Aniston about the new season of "The Morning Show," her kids cookbook, "Cook With Clydeo," and her hair care line.
Natalie Portman
Jan 28, 2026
Natalie Portman tells Drew about her animated movie "Arco" and plays balloon BTS, revealing tidbits about her biggest film roles.