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Season guide

The Big C: Season 2

13 episodes Premiered Jun 27, 2011
Previously on The Big C

Season 2 Lore Primer

Key plot threads, lore context, and character stakes you need to remember before diving into this season.

  • ⚡ Directly follows the overarching narrative developments of The Big C Season 1.
  • ⚡ Faction dynamics and core character alliances shift under escalating external stakes.
  • ⚡ Crucial mysteries introduced previously reach key turning points and narrative reckonings.
  • ⚡ Sets up serialized story arcs that build directly toward the climactic season finale.
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Season 2 Episodes

Episode Guide

🛡️ SPOILER SHIELD

Season 2 Progress Shield

Future titles & synopses blurred. Tap "Reveal" on any card to peek.
Binge Efficiency Engine

Season 2: Filler vs. Essential Canon

Filter episodes by narrative weight. Focus on essential mytharc and skip standalone side quests.

23%
77%
Mytharc (3): Crucial lore & season climaxes
Core (10): Character development & subplots
Side Quest (0): Standalone / filler
S2·E1 Mytharc

Losing Patients

Jun 27, 2011

Cathy seeks a second opinion, causing a strain on her relationship with Dr. Todd; Sean learns about his sister's cancer while adjusting to life with a pregnant Rebecca; Adam sees a

S2·E2 Core

Musical Chairs

Jul 4, 2011

Frustrated at not being able to land a spot in the clinical trial of a new treatment by a respected oncologist, Cathy resorts to supernatural aid; Sean becomes assertive around the

S2·E3 Core

Sexual Healing

Jul 11, 2011

Cathy and Paul experience frustrations in bed and with the help of their new house mate Andrea, realize they need to set some patient-caregiver limits; Rebecca is put off by the ne

S2·E4 Core

Boo!

Jul 18, 2011

Cathy is intrigued by Lee, a fellow cancer patient she meets on the first day of her clinical trial; Adam's downward spiral continues with a fight at school and refusal to take res

S2·E5 Core

Cats and Dogs

Jul 25, 2011

Due to Paul's layoff, Cathy starts to pawn her jewelry and meets Lee there as well. Adam gets into a situation that he may need help with to get out of. Sean is kicked out of a mot

S2·E6 Core

The Little c

Aug 1, 2011

Adam's shocking indiscretion threatens Cathy's new job as a swim coach; sparks fly between Andrea and Myk, a Ukrainian coworker that Paul is mentoring; Sean seeks advice on taking

S2·E7 Core

Goldilocks and the Bears

Aug 8, 2011

Lee takes Cathy to a Tibetan doctor to deal with her high blood pressure. Feeling jealousy of Lee, Paul takes Cathy and Lee out for an evening, while Adam interfere with Andrea's d

S2·E8 Core

The Last Thanksgiving

Aug 15, 2011

Cathy invites friends and family to a Thanksgiving dinner, but a long-hidden secret she brings to light causes trouble.

S2·E9 Core

A Little Death

Aug 22, 2011

Rebecca deals with the grief over her miscarriage in an unexpected way which leads Cathy to reconnect with old friends; Andrea's relationship with Myk heats up; Adam is taken by su

S2·E10 Core

How Do You Feel?

Aug 29, 2011

Cathy helps Lee check a few items off his "bucket list;" Poppy takes Adam to her high school reunion; a distraught Sean takes issue with his new neighbors.

S2·E11 Core

Fight or Flight

Sep 12, 2011

After an argument with Lee and a revealing dinner with Dr. Sherman, Cathy (Laura Linney) comes to a major crossroads. Elsewhere, Adam searches for his AWOL uncle and an impulsive A

S2·E12 Mytharc

The Darkest Day

Sep 19, 2011

As Cathy prepares for her trip to Italy, she receives an amicable call from Lee. Elsewhere, Paul uncovers a secret about Myk while Adam discovers one about Poppy.

S2·E13 Mytharc

Crossing the Line

Sep 26, 2011

Cathy is inspired by Lee's passing to ring in the New Year in an unexpected way; burdened by financial issues, Paul tries a new tactic with the insurance agency; Adam makes a surpr

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