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Season guide

The Big C: Season 1

13 episodes Premiered Aug 16, 2010 Updated Jul 21, 2026
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Season 1 Episodes

Episode Guide

🛡️ SPOILER SHIELD

Season 1 Progress Shield

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Binge Efficiency Engine

Season 1: Filler vs. Essential Canon

Filter episodes by narrative weight. Focus on essential mytharc and skip standalone side quests.

31%
69%
Mytharc (4): Crucial lore & season climaxes
Core (9): Character development & subplots
Side Quest (0): Standalone / filler
S1·E1 Mytharc

Pilot

Aug 16, 2010 · 29 min

After being diagnosed with melanoma, Cathy decides to build a pool in her backyard, much to the chagrin of her older curmudgeonly neighbor, Marlene. Cathy's son, Adam, plays pranks

S1·E2 Core

Summer Time

Aug 23, 2010 · 28 min

Cathy learns from Dr. Todd just how little time she has left, and for the first time in her life, starts to appreciate her body. Paul tries to make sense of his wife's request to l

S1·E3 Core

There's No C in Team

Aug 30, 2010 · 28 min

When Cathy's attempt to connect to the people closest to her fails, she signs up for a well-meaning but overbearing cancer support group. Adam rebuffs Cathy's attempts to connect w

S1·E4 Core

Playing the Cancer Car

Sep 13, 2010 · 28 min

Cathy, eager to try on a carefree, impulsive persona, drains her 401K, buys a convertible and imagines what life would be like if she were Dr. Todd's girlfriend. At his therapist's

S1·E5 Core

Blue-Eyed Iris

Sep 20, 2010 · 28 min

Cathy meets someone new to feel sexy again. Meanwhile, Cathy's eccentric brother Sean tries to keep his building and Adam is caught while watching pornography.

S1·E6 Core

Taking Lumps

Sep 27, 2010 · 25 min

Cathy needs a lump on her butt removed and someone to pick her up after surgery. She asks Marlene, who becomes disoriented - so Lenny picks up Cathy instead. Sean moves into Cathy'

S1·E7 Core

Two for the Road

Oct 4, 2010 · 27 min

Cathy and Sean hit the open road to visit their dad. During the trip, Cathy tells Sean she has cancer. Sean falls apart at the news, so Cathy pretends it was a big joke. Adam gets

S1·E8 Core

Happy Birthday, Cancer

Oct 11, 2010 · 28 min

For her birthday, Paul surprises Cathy with a party just when Lenny has invited her to an art opening on the Bahamas. At the party, Cathy's brother begins a fling with Cathy's ecce

S1·E9 Core

The Ecstasy and the Agony

Oct 18, 2010 · 28 min

Dr. Todd tells Cathy that she's been rejected from the clinical trial. Sean sets up Marlene on a date. At a party, Adam gets into a fight with Andrea. Cathy and Lenny take ecstasy

S1·E10 Mytharc

Divine Intervention

Oct 25, 2010 · 28 min

Cathy's unexpected visit to Andrea's home yields many surprises. Later, Cathy seeks spiritual advice at church and while helping around the house. Rebecca calls it quits with Sean

S1·E11 Core

New Beginnings

Nov 1, 2010 · 28 min

Paul seeks support from people at his work place, but gets more than he bargained for. Sean pulls away from Rebecca when it appears she's getting too serious. Cathy, Marlene and Re

S1·E12 Mytharc

Everything That Rises

Nov 8, 2010 · 28 min

Dr. Todd and Cathy go to see the Bee Man to seek non-traditional treatment for her cancer. Paul is overly supportive of Cathy around the house. Sean gives Adam relationship advice

S1·E13 Mytharc

Taking the Plunge

Nov 15, 2010 · 28 min

Rebecca reveals a secret to Sean that reconnects them. Dr. Todd tells Paul and Cathy that the bee therapy did not work. Cathy reconsiders her options. Adam finally shows his softer

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