Grey's Anatomy: Season 4
Season four of Grey's Anatomy, comprising seventeen episodes, continues the ongoing narrative of the series that follows the intertwined personal and professional lives of a group of physicians working at Seattle's Grey Sloan Memorial Hospital. As a continuation of the overarching saga established since the show's debut in 2005, this season maintains the drama‑focused, TV‑14 tone that characterizes the series. Viewer
Season 4 Lore Primer
Key plot threads, lore context, and character stakes you need to remember before diving into this season.
- Grey's Anatomy is a drama series that premiered on March 27, 2005, and follows doctors at Seattle's Grey Sloan Memorial Hospital.
- The show focuses on the personal and professional lives of its ensemble cast of physicians.
- It is rated TV‑14 and has been renewed annually for many years, establishing a long‑running narrative framework.
- Season four consists of seventeen episodes that continue the series' overarching saga.
Season overview
Season four of Grey's Anatomy, comprising seventeen episodes, continues the ongoing narrative of the series that follows the intertwined personal and professional lives of a group of physicians working at Seattle's Grey Sloan Memorial Hospital. As a continuation of the overarching saga established since the show's debut in 2005, this season maintains the drama‑focused, TV‑14 tone that characterizes the series. Viewers see the ensemble of doctors navigating complex medical cases while dealing with the emotional dynamics that arise within the hospital environment. The season builds on the established setting and character relationships, further exploring the challenges inherent to a high‑pressure surgical workplace. By extending the series' long‑running format—renewed annually for two decades—season four reinforces the show's commitment to portraying both the intense clinical responsibilities and the personal growth of its central characters within the Grey Sloan community.
Episode Guide
Season 4 Progress Shield
A Change Is Gonna Come
Sep 27, 2007 · 43 min
Entering their first year as residents, Meredith Grey, Cristina Yang, Izzie Stevens and Alex Karev now have interns of their own to mentor. Among the new interns are George, forced
Love/Addiction
Oct 4, 2007 · 43 min
A patient is in the hospital because they fell asleep in a hazardous situation. A patient's home laboratory blew up in an apartment building and the victims flood the hospital. Ale
Let the Truth Sting
Oct 11, 2007 · 43 min
The doctors meet the world's oldest intern. Marcy brings in her son Henry because she finds his change in behavior suspicious. A patient named Connie may lose her vocal chords unle
The Heart of the Matter
Oct 18, 2007 · 43 min
A face familiar to one of the year-twos shows up and dredges up issues that were never really dealt with. A teen soccer player needs counseling because of his father and surgery fo
Haunt You Every Day
Oct 25, 2007 · 43 min
It's Halloween at Seattle Grace! There may be jokes, pranks, and/or scare tactics. Some of the women form a club based on an experience they all share. A man volunteers for what mo
Kung Fu Fighting
Nov 1, 2007 · 43 min
A patient comes to the ER with a dream and a condition which may prevent him form realizing it. Two patients are competing to win something big. One of them convinces an intern to
Physical Attraction, Chemical Reaction
Nov 8, 2007 · 43 min
Izzie and George's new-founded relationship results in them having bad sex. Callie's Chief Resident position is taken away from her, and Bailey is the humble replacement. Meredith
Forever Young
Nov 15, 2007 · 43 min
There has been a bus crash and the patients are in the ER. Meredith and Derek's relationship gets more complicated when he dates a fellow doctor. Meredith's dad goes to visit her a
Crash Into Me (1)
Nov 22, 2007 · 43 min
An ambulance crash endangers the lives of the paramedics involved, as Meredith and the Chief work on-site to save them, Bailey treats a patient who refuses her help, and Ava return
Crash Into Me (2)
Dec 6, 2007 · 43 min
Meredith works furiously to save a paramedic trapped in an ambulance; Lexie holds the life of a patient in her hands; Derek must rely on a nurse to save a patient; Bailey struggles
Lay Your Hands on Me
Jan 10, 2008 · 43 min
George has a surprise visitor. Bailey's family is falling apart. Derek sorts through what kissing Rose means. Meredith discovers something that doesn't inspire hope or happiness in
Where The Wild Things Are
Apr 24, 2008 · 43 min
Time has passed but not much has changed. Sexual angst still runs rampant in the halls of Seattle Grace. Derek and Rose have been dating and Meredith has noticed the activities of
Piece of My Heart
May 1, 2008 · 43 min
Addison visits Seattle Grace because they need skills that only she has. Rebecca/Ava returns with news for Alex. Meredith and Derek's clinical trial experiences one or two developm
The Becoming
May 8, 2008 · 43 min
The clinical trial continues to make progress. The anti-McSteamy club creates new initiatives but that isn't enough to stop one woman from spending time with him. Christina is affe
Losing My Mind
May 15, 2008 · 43 min
Dr. Wyatt refuses to let Meredith give up on therapy. Alex learns something else about Rebecca. The Chief wants Erica to perform a daring surgery. Christina continues to act strang
Freedom
May 22, 2008 · 86 min
A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.
Freedom (2)
May 22, 2008
A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someone.