A team of US surgeons says they have successfully transplanted pig kidneys into humans. which they hope will eventually lead to a solution to the problem of organ shortages.
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The patients who received this kidney transplant were in a brain death state, that is, a patient with no chance of recovering back to normal. but still with life support
Kidneys transplanted from pigs that have been genetically modified to inhibit the body’s perception of it as “Foreign thing” and rejected by the body
The trial has not been published in a journal or reviewed by a panel of experts in the field. However, the team of surgeons plans to present their work to gain academic recognition.
The experts said This is the most advanced experiment in the medical field. Previously, the same experiment had only been done in mammals. But this is the first human transplant.
However, pig organ transplantation is not a new concept. Because pig heart valves are widely used in humans. And their organs are already the right size for the human body.
It took a team of surgeons 2 hours into the surgery at New York University’s Langone Health Center. To connect kidneys from donor pigs to blood vessels of recipients who are brain-dead patients. to see if organs will function normally or be rejected when transplanted into humans
They closely monitored their kidney function two and a half days after the surgery. passed many tests
Dr. Robert Montgomery, lead researcher told the BBC that “We noticed that Pig kidneys function similarly to human kidney transplants. And it also seems to fit the body as well as the normal human kidney.”
“It’s working normally and doesn’t seem to be rejected by the body.”
The surgeon also transplanted some of the pig’s thymus gland along with the kidney. They think the thymus may help stop the human body from rejecting pig kidneys in the long run. By acting to eliminate immune cells that may escape to fight the pig’s tissues.
Dr Montgomery, also a former heart transplant recipient, said finding replacement organs for those awaiting organ donation was an urgent need. Although he admits that his work remains controversial.
“The original concept of Some people have to die for the other to live is no longer valid.”
“I definitely understand the concern. and I can say About 40% of patients are now waiting to receive an organ donated and die before they can receive the organ.”
“We have pigs as a food source. We use pigs to treat diseases such as heart valves or to make medicine. Which I don’t think is that different.”
He said this was just preliminary research and further studies are needed. and added that “I think it gives us new confidence that this approach can be applied in the treatment of nursing home patients.”
Families of pig kidney transplant patients who had expressed their intention to be an organ donor allow the surgeon to operate on the patient
U.S. Food and Drug Administration The use of genetically modified pig organs has been approved for this type of research.
Dr. Montgomery believed that within a decade Other pig organs, such as the heart, lungs and liver, can also be used in humans who need organ transplants.
Dr. Maryam Kosrawee, a nephrologist and intensive care unit “An animal-to-human organ transplant is something we have been studying for decades. And it is very interesting to see the medical team moving forward.”
But from an ethical point of view, she said, “Just because we can That doesn’t mean we should. I think the wider medical community has to answer these questions first.”
A spokesman for the NHS Blood and Transplant Office said matching human donors is still a top priority for now and “some time is needed before organ transplants.” From animals to humans, it can actually be used widely.”
“While researchers and medical teams continue to do their best to increase the chances for patients who need an organ transplant We still want everyone to make the decision to become an organ donor. and inform families of what they need if they can become organ donors.”
news BBCThai published on the website fresh news It is a collaboration of two news organizations.